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Selective Acetylcholinesterase Inhibitor 1953-04-4 Galantamine Hydrobromide
Name:Galantamine Hydrobromide Galantamine Hydrobromide Synonyms: NIVALIN;NIVALIN, HBR;4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-6H-BENZOFURO[3A,3,2-EF][2]BENZAZEPIN-6-OL HYDROBROMIDE;GALANTAMINE HBR;GALANTAMINE HYDROBROMIDE;GALANTHAMIDE HYDROBROMIDE;GALANTHAMINE HBR;GALANTHAMINE HYDROBROMIDE Galantamine Hydrobromide CAS: 1953-04-4 Galantamine Hydrobromide MF: C17H22Br NO3
Galantamine Hydrobromide MW: 368.27 Galantamine Hydrobromide EINECS: 217-780-5 Product Categories: Alkaloids;Alkaloids (Others);Biochemistry;Functional Products;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Acetylcholine receptor;API;Chiral Reagents;Reminyl;Other APIs;Pharmaceutical intermediates MP 256 °C
Storage temp. −20°C Chemical Properties White to Off-White Powder Usage A selective acetylcholinesterase inhibitor. A therapeutic agent for the treatment and prevention of Alzheimer's disease and other diseases resulting from reduced neuronal metabolism. Usage Alzheimer treatment;Cholinesterase inhibitor Usage anticholinesterase, analgesic, antiAlzheimer
Galantamine Hydrobromide Description: Galantamine hydrobromide is the hydrobromide salt of galantamine and is a cholinesterase inhibitor can be extracted from Amaryllidaceae Lycoris plant. The III-phase clinical trials in the United Kingdom in 1998 have showed that this drug had dual mechanism of action of both inhibiting acetylcholinesterase and regulating nicotinic receptors. Therefore, galantamine can improve the cognitive abilities of Alzheimer's patients and has been already applied as the drug of the treatment of mild to severe Alzheimer's disease (AD) drugs and has entered into market in EC countries. "Chinese Pharmacopoeia" has included the both the raw material and injection of galantamine hydrobromide. It is clinically mainly used for the treatment of poliomyelitis (polio) sequelae, muscular dystrophy and myasthenia gravis. It can be used to substitute neostigmine methyl-sulfate for antagonism of tubocurarine but with weak performance with the usage amount being ten times as high as the usage amount of neostigmine methyl-sulfate. Intravenous injection of 0.5 mg/kg of galantamine hydrobromide can quickly reverse the central anticholinergic effects caused through injection of hydrobromide. It can also be used for treating children cerebral palsy, traumatic sensorimotor disorders, multiple neuritis and radiculitis. Galantamine Hydrobromide Application : It can be used for the treatment of neurological diseases and trauma-induced movement disorders, multiple neuritis, and radiculitis.
Cholinesterase inhibitors can reverse the process of -induced amnesia.
